The error message given if the DDM TCP/IP server is not started is CPE3425.
A remote host refused an attempted connect operation.You can also get this message if you specify the wrong port on the Add Relational Database Directory Entry (ADDRDBDIRE) or the Change Relational Database Directory Entry (CHGRDBDIRE) command. For a DB2 Universal Database™ for iSeries™ server, the port should usually be *DRDA (the DRDA® well-known port of 446). However, if you have configured port 447 for use with IPSec, you might want to use that port for transmitting sensitive data. If you are using a DRDA client that supports Secure Sockets Layer (SSL), you must connect to port 448 on the server.
To start the DDM server on the remote server, run the Start TCP/IP Server (STRTCPSVR) *DDM command. You can request that the DDM server be started whenever TCP/IP is started by running the Change DDM TCP/IP Attributes (CHGDDMTCPA) AUTOSTART(*YES) command.